Friday, February 27, 2015
Distinct plasma immune signatures in ME/CFS
No, it's NOT all in our heads.....
Distinct plasma immune signatures in ME/CFS are present early in the course of illness | Science Advances - Significant resear
distinct alterations in plasma immune signatures early in the course of ME/CFS (n = 52) relative to healthy controls (n = 348) that are not present in subjects with longer duration of illness (n = 246). Analyses based on disease duration revealed that early ME/CFS cases had a prominent activation of both pro- and anti-inflammatory cytokines as well as dissociation of intercytokine regulatory networks. We found a stronger correlation of cytokine alterations with illness duration than with measures of illness severity, suggesting that the immunopathology of ME/CFS is not static.