Doctors have long suspected brain inflammation as a potential cause, but no definite traces of it had been detected. New research, in the June issue of the Journal of Nuclear Medicine, shows for the first time distinct increases in inflammation in particular regions of CFS patients' brains.
Yasuyoshi Watanabe, director of the RIKEN Center for Life Science Technologies and professor of physiology at Osaka City University Graduate School of Medicine, and his colleagues studied positron emission tomography (PET) scans of the brains of 10 health controls and nine patients with CFS. "Many researchers and clinicians, including our group, thought of this before, but apparently no one tried it using PET," Watanabe says.
The research team found increases in inflammatory markers in regions including the amygdala, thalamus and midbrain in CFS patients who had more severe cognitive troubles. They found more of these markers in thalamus and cingulate cortex in individuals who reported worse pain. And they found higher traces of inflammation in the hippocampus in patients with severe depression.
Actually, I'll dispute that -- Hillary Johnson describes using brain scans in "Osler's Web" already ... but now it's out there in commonly-read literature, not just CFS circles.
MAY IS CFS/FIBROMYALGIA AWARENESS MONTH!
www.CFSfacts.org -- where we give you the facts and dispel the myths (also on Facebook)
Myths, with research cites: http://www.aacfs.org/images/pdfs/myths.pdf
Newest research blog: http://cfs-facts.blogspot.com/