Wednesday, March 26, 2014

2014 IACFS/ME Conference -- Klimas

she's using immunomodulatory drugs
 
she's now at an osteopathic medical school, moved from an allopathic medical school -- her treatment is very integrative
 
look at the genes that are turned on/off in response to exercise
9 million bits of data
computational biologists say that's not much data -- they do modeling analysis
 
Homeostatic Drive in Perpetuation of Complex Chronic Illness, by Craddock, et al.
 
3 minutes of exercise, 10 pathways activate -- this is NOT NORMAL
 
She's mining drug action data -- what drugs do what in other illnesses with similar abnormalities
 
immune activation and functional defects are dysfunctional
 
"Rituximab opened the door to autoimmune thinking"
 
amantidine works on MS fatigue -- low dose naltrexone, too -- CoQ10
 
Isoprinosone (Immunovir from Newport Pharmacy, Inosine is OTC here) -- available in Canada
 
Oxidative stress:
glutathione
N-acetylcysteine
alpha lipoic acid
NADH
 
Also:
B vitamins
C
magnesium
sodium
zinc
L-tryptophan
L-carnitine
CoQ10
essential fatty acids
 
Q&A:
there is a close link between the immune system and the autonomic system
 
In a normal person, exercise brings extra energy to cells, but we turn those pathways OFF
a VO2Max test will tell you your threshold pulse, but then you have to rest all the way back to resting baseline heart rate
 
"if you can prevent flu, you should" -- if you've been OK with the flu shot in the past, by all means get it
 
 
 
 
 

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