Monday, July 15, 2013

CFS and IBS

Source: Clinical and Experimental Gastroenterology
Vol. 6, Pages 101-107
Date: July 3, 2013
URL: http://www.dovepress.com/getfile.php?fileID=16639
http://www.dovepress.com/chronic-fatigue-in-patients-with-unexplained-self-reported-food-hypers-peer-reviewed-article-CEG


Chronic fatigue in patients with unexplained self-reported food
hypersensitivity and irritable bowel syndrome: validation of a
Norwegian translation of the Fatigue Impact Scale
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Ragna Lind(1,*), Arnold Berstad(2), Jan Hatlebakk(1,3), Jorgen
Valeur(2)
1 Department of Medicine, Haukeland University Hospital, Bergen,
2 Unger-Vetlesen Institute, Department of Medicine, Lovisenberg
Diakonale Hospital, Oslo,
3 Department of Clinical Medicine, University of Bergen, Bergen,
Norway
* Correspondence: Ragna Lind
Department of Medicine, Haukeland University Hospital, N-5021
Bergen, Norway. Tel +47 5597 6103. Email ragna.lind@med.uib.no

Received: 26 March 2013
Accepted: 28 May 2013
Published: 04 July 2013


Abstract

Background
Patients with unexplained self-reported food hypersensitivity and
irritable bowel syndrome (IBS) suffer from several health complaints,
including fatigue. The aim of the present study was to validate a
Norwegian translation of the Fatigue Impact Scale (FIS), and to assess
the impact of fatigue in patients with self-reported food
hypersensitivity and IBS, as compared with healthy controls.

Methods
Thirty-eight patients with unexplained self-reported food
hypersensitivity and IBS, who participated in the validation of the
FIS completed the following additional questionnaires: the Short Form
of Nepean Dyspepsia Index for assessment of quality of life, the
Subjective Health Complaint Inventory, and questionnaires for
diagnosis and severity of IBS. Impact of fatigue was studied in 43
patients with unexplained self-reported food hypersensitivity, 70%
diagnosed with IBS, and 42 healthy controls.

Results
Cronbach's alpha for the FIS was 0.98, indicating excellent agreement
between individual items. Scores on the FIS correlated with scores on
the Short Form of Nepean Dyspepsia Index (r=0.50, P=0.001),
indicating good convergent validity, and were higher in patients
(median 85.0, interquartile range 36.8-105.3) than in controls (median
14.0, interquartile range 3.0-29.0, P=<0.0001).

Conclusion
The Norwegian translation of the FIS performed excellently
in patients with unexplained self-reported food hypersensitivity and
IBS, with patients reporting significantly more impact of chronic
fatigue than healthy controls.

Keywords: irritable bowel syndrome, fatigue, food hypersensitivity,
quality of life

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(c) 2013 Dove Press

1 comment:

Hayley-Eszti Szucs said...

Very interesting, Thanks for sharing xx