Turk Kardiyol Dern Ars. 2013 Jan;41(1):75-83. doi: 10.5543/tkda.2013.44420.
Neurocardiogenic syncope and associated conditions: insight into
autonomic nervous system dysfunction.
Kossaify A, Kallab K.
Department of Syncope and Electrophysiology, ND Secours/USEK
University Hospital, Byblos, Lebanon. firstname.lastname@example.org.
Neurocardiogenic syncope is known to be associated with autonomic
nervous system dysfunction, although the mechanism has not been
entirely elucidated. In this study, we sought to highlight the
pathogenic role of the autonomic nervous system in neurocardiogenic
syncope and to review the associated co-morbidities known to have a
dysautonomic basis. Herein we discuss migraine, orthostatic
hypotension, postural orthostatic tachycardia syndrome, endothelial
dysfunction, chronic fatigue syndrome, and carotid sinus
hypersensitivity with a focus on the pathogenic role of the autonomic
nervous system and any consecutive clinical implications. Other
conditions, such as pre-syncopal heart rate acceleration and/or
instability and pre-syncopal breathing instability, which occur during
a tilt test, are discussed in the same perspective.
PMID:23518945[PubMed - in process]