Thursday, June 28, 2012

Help for Zombies — A Special Report

Help for Zombies — A Special Report

Dear Readers,

Have you been feeling like a zombie lately? You're not alone! But new research is again showing more reason for hope.

In a new study published yesterday in the Open Pain Journal involving 53 different health clinics, 257 people with CFS and fibromyalgia who felt like zombies were fed 5 grams of ribose 3 times a day for 3 weeks [Editor's note: the zombie part is just my assumption;-)]. At the end of the three weeks, participants' energy levels increased by an astounding average of 61%. In addition, sleep, pain, mental clarity, and overall well-being improved.

This study confirmed what we had seen in an earlier study. Here are the numbers:

203 people completed the 3 week trial. Consuming D-ribose led to both statistically (p<.0001) and clinically highly significant average improvements in all categories:

  • 61.3 % increase in energy
  • 37% increase in overall well-being
  • 29.3% improvement in sleep
  • 30% improvement in mental clarity
  • 15.6% decrease in pain

At the end of the study, improvement was continuing to increase, suggesting that continued supplementation with ribose would be associated with an even greater improvement. The current double-blind placebo-controlled study, which is being done at eight research centers, is being extended to 12 weeks to see at what point the benefit levels out.

So for those of you feeling like zombies, here's your chance to get a big boost in energy — so you no longer have to feel like you're in a "Night of the Living Dead" movie!

Read more »

Love & blessings,

Dr. T

Happy Anniversary PANDORA!

Deadline July 31

CFS Solutions of West MI has created a groupcard. It's to congratulate
PANDORA on it 10 year anniversary. Could you please post this to your site
so more people can sign the card?


Toby Vokal
*Group Leader*
*ME/CFS & FM Shoreline Chapter*

Wednesday, June 27, 2012

The latest from Dr. Peterson

Just The Facts:The median age of death for cancer in
the U.S. is 72, vs an average age of 47.8 for CFS/ME, the average age of death for suicide in the U.S. is 48, vs an average age of 39.3 for CFS/ME, and the average age of heart failure is 83.1, vs an average age of 58.7 years for CFS/ME. What this suggests is based on Jasons Article is that those from the memorial list who did die of cancer, su
icide, and heart failure were much younger than what would have been expected from the general population, which means that CFS/ME might have increased the risk of death for at least this sample.Visit today to fund Your Research Now!

Tuesday, June 26, 2012

Can I mix coffee with my meds? – - Blogs

Dr Elizabeth Dowsett "Betty" (1920 - 2012)

Submitted by Colin Barton <>]

Dr Elizabeth Dowsett  "Betty" (1920 - 2012)

It is with great sadness we learnt of the death of Betty Dowsett on 14
June 2012 at an age of ninety one, in a nursing home in Cambridge, where
she had lived for some years.

Betty was born in Newport, Gwent, and studied medicine at Edinburgh
University.She worked as a general practitioner in London, and then
after further studies, became a consultant microbiologist.

It is well known that she had built up a huge and unique expertise in
ME, helping thousands of patients from the 1960s onwards.She worked
with the late Dr John Richardson, and the late Dr Melvin Ramsey, and
continued that thread of clinical and research interest in the times
when there was a general neglect of this patient group.

I first came into personal contact with Betty Dowsett during the 1980s,
when her thriving ME Support Group amalgamated with my NHS neurology
clinic at the old Harold Wood Hospital in Essex.

We both recognised that there was a paucity of care available in the
NHS, for many patients with ME. This lead us to set up the National ME
Centre as a diagnostic and support service, for those who were unable to
receive, at that time, appropriate advice through NHS services.

Betty Dowsett and I shared a commonality of thought about some aspects
of ME (you will note I do not use the word CFS on this occasion, out
of respect for her, because she felt it was an inappropriate diagnostic
term).What we shared was the conviction that even if a medical
condition, such as ME, was not understood in terms of underlying
mechanisms, those with ME should be offered advice and support, based
on the best evidence available at the time.In this regard Betty Dowsett
was an example of best clinical practice.

Betty Dowsett carried out her own unique and extensive research into
ME. I remember her impressive review of symptoms in a group of four
hundred patients with ME, which drew my attention of how common
neurological symptoms were part of the core phenomenology.

In addition, her work demonstrated the social impact of ME in young
patients, and the effect this had on their education.This research was a
beacon which catalysed changes in attitudes.

Unfortunately, in the modern era, most clinicians will only travel on a
comfortable road.Betty Dowsett was an individual who chose her own path,
if she felt it was in the interest of her patients.She was resistant to
what she perceived as unfair criticisms, argued vociferously at every
level for the welfare and interests of those who were unfortunate to
suffer with ME.

I understand from others that Betty promised Dr Melvin Ramsey before his
death, that she would continue his work.She kept that promise to the
very end.I was proud to have known her, and be associated with her.

Professor Leslie J Findley
Consultant Neurologist and
Clinical Director
Essex Fatigue Services Ltd_

Biological underpinnings of commonalities in depression, somatization, and CFS

Note: Tryptophan is the key ingredient in making serotonin; without
it, serotonin won't be produced.

The issue with connecting somatization with these pathways is that
somatization is a concept based in many cases on proving a negative.
There is currently no objective means of proving the concept exists
thus connections are assumed.  As always the cautions regarding
definitions used are key.

Med Hypotheses. 2012 Jun;78(6):752-6. Epub 2012 Mar 23.

Biological underpinnings of the commonalities in depression,
somatization, and Chronic Fatigue Syndrome.

Anderson G, Maes M, Berk M.
CRC, Rm 30, 57 Laurel St., Glasgow, G11 7QT Scotland, United Kingdom.


Somatization is a multisomatoform disorder characterized by medically
unexplained, functional or psychosomatic symptoms. Similar somatic
symptoms are key components of depression and Myalgic
Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).

This paper reviews the evidence that such symptoms are organically
based. We use the term "physio-somatic" to describe these symptoms.

Inflammation, cell-mediated immune (CMI) activation and alterations in
the tryptophan catabolite (TRYCAT) pathway are associated with the
physio-somatic symptoms of depression, ME/CFS and/or somatization.
Proinflammatory cytokines, decreased tryptophan and aberrations in
TRYCATs may cause physio-somatic symptoms, such as fatigue, autonomic symptoms, hyperalgesia and somatic presentations.


The data suggest co-ordinated and interacting biological pathways
driving the occurrence of physio-somatic symptoms across these three
disorders, giving a biologically validated "pathway phenotype".

These data have far-reaching implications for DSM-IV diagnostic
conceptualizations of somatization (and ME/CFS) suggesting the
presence of an emerging organic explanation.

Future research should focus on the role of immune regulation, and
co-ordination, of neuronal activity and, through larger data sets,
ultimately creating new, biologically validated classification rules.
These data have implications for the development of novel therapies
utilizing these insights, buttressing the role of psychotherapy in
psychosomatic presentations.

Copyright © 2012 Elsevier Ltd. All rights reserved.

Additional research in this area;
* * *
I had great improvement when I started to take 5HTP (tryptophan).