MM: You mentioned you were on antidepressants for just a few days and [they] didn't agree with you. You say there are people out there being treated with antidepressants who might not actually be helped by them and actually may be worse off. Why do you think antidepressants sometimes don't help and why do so many people believe that they do?
AW: Well, there's an accumulating body of research that shows that SSRIs [selective serotonin reuptake inhibitors, a type of antidepressant medication] may not work any better than placebos, even for severe depression, and that maybe only in very, very severe depression is there in an advantage. One expert says that it may not matter what you do as long as you do something, and it doesn't matter WHAT you do — it could be going into therapy, taking antidepressants, making a lifestyle change — just doing something that shifts that mental energy. It changes your mood and that's what really produces a benefit.
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Or maybe, people are made worse because they're being given anti-depressants when they don't actually have depression. A-Ds make me sicker, because I'm not depressed -- I have a post-viral neurological condition.