Friday, February 11, 2011

Fatigue Scales and CFS

This is a really good article, fulltext can be found here-
http://www.dsq-sds.org/article/view/1375/1540

---------- Forwarded message ----------
From: kelly <kellylatta66@gmail.com>
Date: Fri, Feb 11, 2011 at 7:39 AM
Subject: [CO-CURE] RES: Fatigue Scales And Chronic Fatigue Syndrome:
Issues Of Sensitivity And Specificity
To: CO-CURE@listserv.nodak.edu


Note: Some fatigue scales such as the Chalder Scale have a ceiling effect
rendering it ineffective specifically for measuring post exertional fatigue


Disability Studies Quarterly, Vol 31, No 1 (2011)



Fatigue Scales And Chronic Fatigue Syndrome: Issues Of Sensitivity And
Specificity



*Leonard Jason, Jason Meredyth Evans, Molly Brown, Nicole Porter, Abigail
Brown, Jessica Hunnell, Valerie Anderson, Athena Lerch*

 Abstract



Few studies have explored issues of sensitivity and specificity for using
the fatigue construct to identify patients meeting chronic fatigue syndrome
(CFS) criteria.

In this article, we examine the sensitivity and specificity of several
fatigue scales that have attempted to define severe fatigue within CFS.


Using Receiver Operating Characteristic (ROC) curve analysis, we found most
scales and sub-scales had either significant specificity and/or sensitivity
problems.


However, the post-exertional subscale of the ME/CFS Fatigue Types
Questionnaire (Jason, Jessen, et al., 2009) was the most promising in terms
of specificity and sensitivity.


Among the more traditional fatigue scales, Krupp, LaRocca, Muir-Nash, and
Steinberg's (1989) Fatigue Severity Scale had the best ability to
differentiate CFS from healthy controls.

Selecting questions, scales and cut off points to measure fatigue must be
done with extreme care in order to successfully identify CFS cases.

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