Wednesday, January 5, 2011

XMRV: A Human Retrovirus With Unknown Pathogenic Potential, Not A Lab Contaminan

  XMRV: A Human Retrovirus With Unknown Pathogenic Potential, Not A Lab Contaminant

The recent proclamation that "XMRV is not the cause of CFS," came from an individual who did laboratory experiments to show how PCR experiments can become contaminated. These results have nothing to do with the reality of a disease or the methods used by those who have detected XMRV in the blood and tissue of patients found to be infected. The positive studies, which cannot be explained away by PCR experiments, are those which have used multiple methods to show that XMRV is a live replicating gamma retrovirus in human blood and tissue samples using the gold standard methods of viral isolation and antibody testing, in addition to PCR.  Authors of the positive XMRV studies have been extremely careful not to claim causality, realizing that more scientific research is required to make such a statement. However, one fact still remains clear. Not one of the negative studies changes the results of the scientific research done by Lombardi et al., Lo et al., Urisman et al., and Schlaberg et al. Most significantly, the recent Retrovirology publications failed to address the most important pieces of scientific evidence of human infection in the previous XMRV studies, including the fact that XMRV positive patients produce human antibodies to gamma retroviruses, XMRV integrates into human tissues, and infectious virus has been cultured from the blood of hundreds of patients with a diagnosis of Chronic Fatigue Syndrome and M.E. Humans do not make antibody responses to mouse DNA sequences from contaminated lab experiments. WPI's collaborative research projects are revealing the infectious and inflammatory nature of neuro-immune diseases, providing strong evidence against the use of CBT and exercise therapy as rational "treatments" for those who are ill. Such knowledge underscores the urgent need for much more private and federal funding of biological research to provide diagnostic tests and effective drug therapies for the millions who are ill, stop the spread of infectious retrovirus(es), and end the devastating cycle of disease.
Annette Whittemore, President, Whittemore Peterson Institute
Related Links:
*
Detection of an Infectious Retrovirus, XMRV, in Blood Cells of Patients with Chronic Fatigue Syndrome
Judy A. Mikovits et al, 10.1126/science.1179052, Science Express
*
Presence Of Murine Leukemia Virus Found In Chronic Fatigue Syndrome Patients
FDA Press Release
*
Detection of MLV-related virus gene sequences in blood of patients with chronic fatigue syndrome and healthy blood donors (FULL TEXT)
Shyh-Ching Lo, Harvey J. Alter et al PNAS
*
Red Cross Bars Chronic Fatigue Syndrome (ME/CFS) Patients From Donating Blood
Rob Stein, The Washington Post

READ THE NEWS ON ONE CLICK
http://www.theoneclickgroup.co.uk

No comments: