Sunday, January 2, 2011

Sleep, CFS and Fibromyalgia

http://www.ncbi.nlm.nih.gov/pubmed/21096267

Conf Proc IEEE Eng Med Biol Soc. 2010;1:5391-4.

Sleep stage transitions in chronic fatigue syndrome patients with or
without fibromyalgia.
Kishi A, Natelson BH, Togo F, Struzik ZR, Rapoport DM, Yamamoto Y.

Educational Physiology Laboratory, Graduate School of Education, The
University of Tokyo, 113-0033, Japan.

Abstract
Chronic fatigue syndrome (CFS) and fibromyalgia (FM) are medically
unexplained conditions that share considerable overlapping symptoms,
including sleep-related complaints. However, differences between the
two conditions have been reported, and we hypothesized that dynamic
aspects of sleep, recently attracting scientific interests, would be
different in the two groups of patients. We thus study transition
probabilities between sleep stages of CFS patients with or without FM.
Subjects were 26 healthy controls, 14 CFS patients without FM (CFS
alone) and 12 CFS patients with FM (CFS+FM) - all women. We studied
transition probabilities between sleep stages (waking, REM sleep and
Stage I, Stage II and slow-wave sleep (Stage III+IV)). We found that
probabilities of transition from REM sleep to waking were
significantly greater in CFS alone than in controls; we have reported
previously this sleep disruption as the specific sleep problem for CFS
alone [Kishi et al., 2008]. Probabilities of transitions from waking,
REM sleep and Stage I to Stage II, and those from slow-wave sleep to
Stage I, were significantly greater in CFS+FM than in controls; the
former might indicate increased sleep pressure in CFS+FM and the
latter may be the specific sleep problem of CFS+FM. These results
suggest that CFS and FM are different illnesses associated with
different problems of sleep regulation.

PMID: 21096267 [PubMed - in process]

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