Monday, November 2, 2009

We made Science Magazine's Top Ten!

The XMRV news made one of the top ten news items in the monthly "Science" Roundup.
Viral Link to Chronic Fatigue

As its name implies, chronic fatigue syndrome (CFS) is characterized by debilitating fatigue that can persist for many years. Although often linked to immune system dysfunction, the cause(s) of the disorder remain mysterious. In a Report in the 23 Oct 2009 Science (published online 8 Oct), Lombardi et al. presented a potential new lead. The team found that blood samples from 68 of 101 CFS patients contained DNA from a human retrovirus called xenotropic murine leukemia virus–related virus (XMRV), which is genetically similar to a murine leukemia virus. Cell culture assays confirmed that XMRV derived from CFS patient plasma and from T and B lymphocytes was infectious. Interestingly, nearly 4% of the 218 healthy donors tested were also positive for XMRV, which suggests that the virus may be present in a significant proportion of the general population. As noted in an accompanying Perspective by J. M. Coffin and J. P. Stoye, CFS is not the first human disease to which XMRV has been linked: it has also been linked to an aggressive form of prostate cancer (see the related News story by S. Kean in the 9 Oct issue). Both laboratory and epidemiological studies are needed to determine whether the virus plays a causative role in these diseases



1 comment:

María Fernanda said...

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