Tuesday, November 24, 2009

Expert Answers on Chronic Fatigue Syndrome - Consults Blog - NYTimes


Are There Two Viruses Linked With Chronic Fatigue Syndrome?


Dr. Klimas: I really want to know more about what you think of the specific findings of Dr. DeFreitas. Do you think there are two retroviruses associated with Cfids? I know there needs to be more study, but do you have an educated guess as to how they interact and if they are causative or just epiphenomena?

For example, if this were solely hypocondriasis or conversion disorder, I would want to know so I could start therapy on it.
Justin Reilly


Dr. Klimas responds:

Elaine DeFreitas's work and that of Dr. Michael Holmes of New Zealand both involved scanning electron micrographs of viruses. Their findings look a great deal like those that were published in the recent Science article by Dr. Lombardi and colleagues, which Ms. Grady wrote about in The Times,) that found a possible link between chronic fatigue syndrome and the XMRV retrovirus. Could they be looking at the same virus? I don't really know, because I am not a laboratory virologist. But it makes good sense to me.

I remember in the early 1990s a member of our laboratory, Dr. Roberto Patarca, found evidence of production of an enzyme called reverse transcriptase in our cell cultures, more evidence of an active retroviral infection. So the key thing now is for another reputable lab to find the same thing in chronic fatigue syndrome. Then we will see what happens next.


Online said...

Cool Posting!!

Bartholomew said...

Very interesting. I am chronic fatigue doctor in practice. I gained some important information about this topic.

CFS Facts said...

The latest research is teaching ALL of us some important information about this topic.

Confirming things that patients have been saying for years, and doctors have been poohpoohing because "it makes no sense" to them. When I was too sick to think well enough to argue with him, I had a doctor tell me that it was impossible for a virus I had in February to still be affecting me in November; guess he never heard of polio or about shingles recurring decades after chicken pox.

In fact, no symptom in CFS is "impossible", if the doctor is willing to think outside the box. There *are* other conditions where exercise is inadvisable. There *are* other conditions where a virus causes lifelong aftereffects.

And, thank God, the latest research is proving what we've been saying for 25 years.