Saturday, June 6, 2009

Returning to the Infectious Roots of CFS

Patients wishing to contact the CDC regarding the need to return
ME/CFS research to its infectious roots may wish to cite the following
study (without the explanations which are solely for informational
purposes for patients without a medical terminology background). It
should be noted that neither depression or anxiety are listed perhaps
because patients were not yet stigmatized.

Preventive medicine is one of the pillars of the CDC: Possibly
billions of dollars in economic losses could be mediated by
preventative measures such as administration of antivirals or even
genetic therapy at some point in the future, but that takes research

Symptoms and Signs of Chronic Fatigue Syndrome
Anthony L. Komaroff and Dedra Buchwald
Reviews of Infectious Diseases, Vol. 13, Supplement 1. Considerations
in the Design of Studies of Chronic Fatigue Syndrome (Jan. - Feb.,
1991), pp. S8-S11

This review summarizes the symptoms and signs seen in patients with
Chronic Fatigue Syndrome. It is based on the experience with two
cohorts of -510 patients with chronic debilitating fatigue and on the
reported experience of other investigators with similar patients.

The most characteristic symptoms of CFS are:

The sudden on-set of an infectious – type illness,

Subsequent chronic and debilitating fatigue,

postexertional malaise (post-exertional malaise is a period of intense

Many patients also have:

Recurrent fevers (infections are the most common causes of higher than
normal body temperature)

Pharyngitis (Pharyngitis is inflammation of the pharynx, which is in
the back of the throat, between the tonsils and the voicebox (larynx).
Viruses are the most common cause of pharyngitis. Many different
viruses can cause pharyngitis)

Adenopathy (Large or "swollen" lymph nodes. In the United States,
common viral and bacterial infections are overwhelmingly the most
common cause of adenopathy)

Myalgias (pain in a muscle or group of muscles - without a traumatic
history is often due to viral infections),

Sleep disorders (pro inflammatory cytokines, which are one of the
body's immune responses to infection, also cause sleep dysfunction.)

Cognitive impairment

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