Journal: Open Neurol J. 2009 Feb 27;3:13-23.
Authors: Thomas M, Smith A.
Affiliation: Centre for Occupational and Health Psychology, School of
Psychology, Cardiff University, UK.
NLM Citation: PMID: 19452031
This study addresses, among other things, the debate as to whether
cognitive deficits do occur with a diagnosis of Chronic Fatigue
Syndrome (CFS). Previous studies have indicated a potential mismatch
between subjective patient ratings of impairment and clinical assessment.
In an attempt to tackle some of the methodological problems faced by
previous research in this field, this study recruited a large sample
of CFS patients where adequate diagnosis had been made and
administered an extensive battery of measures. In doing so this study
was able to replicate previous published evidence of clear cognitive
impairment in this group and demonstrate also that these deficits
occurred independent of psychopathology.
The conclusion drawn is that cognitive impairments can be identified
if appropriate measures are used. Furthermore, the authors have shown
that performance changes in these measures have been used to assess
both efficacy of a treatment regime and rates of recovery.
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