Monday, November 24, 2014

Brains of People with Chronic Fatigue Syndrome Offer Clues


Many patients are still told to seek psychiatric help. But two recent studies — one from investigators at Stanford a few weeks ago and another from a Japanese research team published earlier this year — have found that the brains of people with chronic fatigue syndrome differ from those of healthy people, strengthening the argument that serious physiological dysfunctions are at the root of the condition.

"You've got two different groups that have independently said, 'There's something going on in the brain that is aberrant,' " said Leonard Jason,

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It's "all in our heads", but not in the way they thought!



Sunday, November 23, 2014

NIH Categorical Spending -NIH Research Portfolio Online Reporting

Headaches get 5x the research funding as ME/CFS.  Otitis media (ear infection) gets 3x as much funding.  Cancer gets 1000x as much funding as ME/CFS.  Even the mild annoyance of hay fever gets twice as much funding as our disabling illness!
The inequalities are horrifying.
We get $5M; MS, which is fairly similar in symptomatology, gets $115M.
If anyone wants to know why you're not taking any medications, not having any improvement, just point them to this chart.

Saturday, November 15, 2014

Check out Onward Through the Fog: "Government unreasonable": Judge Vince Chha

In the Court's order, the Judge noted:
Ms. Burmeister is clearly the prevailing party in the litigation. Moreover, as outlined in the order granting Ms. Burmeister's motion for summary judgment, the government's conduct throughout its dispute with Ms. Burmeister was unreasonable. Ms. Burmeister stood to gain nothing financially from her attempt to obtain documents at issue from the government, and she conferred a benefit on the public through her successful effort to obtain a ruling against the government. [emphasis added]

defendants produced a mere 88 pages, only 22 relating specifically to the IOM (one of them blank), for a very high-priority and extraordinarily controversial $1 million project. It was clear that their search and production of documents was woefully inadequate (as the Court later agreed when it granted my motion for summary judgment). The defendant's subsequent response to my complaint was, once again, late. It was then that I realized that they had no intention of complying with the law in response to my entirely reasonable and very straightforward FOIA request, even faced with a lawsuit.
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Clearly, there's an intentional government cover-up when it comes to CFS.....
What are they hiding?

Wednesday, November 12, 2014

CoQ10 + NADH = improvement?

Does oral Coenzyme Q10 plus NADH supplementation improve fatigue and
biochemical parameters in Chronic Fatigue Syndrome?

Dr. JESUS CASTRO-MARRERO, Ph.D., Prof. Mario D. Cordero, Dr. Maria
Jose Segundo, Naia Saez-Francas, Dr. Natalia Calvo, Dr. Lourdes
Román-Malo, Luisa Aliste, Prof. Tomas Fernandez de Sevilla, Dr. Jose


Chronic Fatigue Syndrome (CFS) is a chronic and extremely debilitating
illness characterized by prolonged fatigue and multiple symptoms with
unknown cause, diagnostic test, or universally effective treatment.
Inflammation, oxidative stress, mitochondrial dysfunction, and CoQ10
deficiency have been well documented in CFS. We conducted an 8-weeks
randomized, double-blind, placebo-controlled trial to evaluate the
benefits of oral CoQ10 (200 mg/day) plus NADH (20 mg/day)
supplementation on fatigue and biochemical parameters in 73 Spanish
CFS patients. This study was registered in
(NCT02063126). A significant improvement of fatigue showing a
reduction in FIS total score (p< 0.05) was reported in treated group
vs. placebo. In addition, a recovery of the biochemical parameters was
also reported. NAD+/NADH (p< 0.001), CoQ10 (p< 0.05), ATP (p< 0.05)
and citrate synthase (p< 0.05) were significantly higher and
lipoperoxides (p< 0.05) were significantly lower in blood mononuclear
cells (BMCs) of the treated group. These observations lead to the
hypothesis that the oral CoQ10 plus NADH supplementation could confers
potential therapeutic benefits on fatigue and biochemical parameters
in CFS. Larger sample trials are warranted to confirm these findings.

Wednesday, October 29, 2014

Study finds brain abnormalities in chronic fatigue patients | News


It's not uncommon for CFS patients to face several mischaracterizations of their condition, or even suspicions of hypochondria, before receiving a diagnosis of CFS. The abnormalities identified in the study, published Oct. 29 in Radiology, may help to resolve those ambiguities, said lead author Michael Zeineh, MD, PhD, assistant professor of radiology.

"Using a trio of sophisticated imaging methodologies, we found that CFS patients' brains diverge from those of healthy subjects in at least three distinct ways," Zeineh said.

Chronic fatigue is real, new brain scans show - Health -

 Stanford researchers found distinct differences between the brains of patients with chronic fatigue syndrome and those of healthy people, according to a study published in Radiology Wednesday. ... Zeineh and his colleagues found several anomalies in the brains of CFS patients, including a reduction in the amount of white matter—a part of the brain that is composed of long fibers which serve as the communication cables between nerve cells.

Sunday, October 26, 2014

I’m Sick But What Is Wrong with Me? | Psychology Today

Research funding for CFS is near the bottom of the heap. Two examples: it receives a fraction of what is allocated for allergy research and even for male pattern baldness, despite the fact that CFS can leave people unable to work and, in many cases, bedbound. I had to give up a productive career due to this illness. Who is forced to leave the workforce due to male pattern baldness?
Another winner from Toni Bernhard